Educational Articles

False Positive Scl-70 Results – A Major Problem in Laboratory Testing

Scl-70 antibody testing can be done by a number of different methods. Historically, Scl-70 antibody testing was mostly done by a technique called double immunodiffusion (ID), which is considered to [...]

January 2nd, 2019|

High Magnification Nailfold Capillary Examination for the Diagnosis of Systemic Scleroderma

Diagnosis of systemic scleroderma can often be very challenging.  Diagnosis is done by a combination of lab tests (ANA/antibodies) and clinical symptoms such as skin thickening, puffy hands, telangiectasias. Additional symptoms [...]

August 2nd, 2018|

New Educational Video: Therapeutic Plasma Exchange as a Treatment for Systemic Sclerosis

We are pleased to announce that the Scleroderma Education Project has just started a new YouTube educational channel.  Our first video is an overview of the research literature on therapeutic plasma [...]

June 29th, 2018|

Safety of Autologous Hematopoietic Stem Cell Transplants (HSCT) in Systemic Sclerosis

For those of you interested in autologous stem cell transplants, this paper was just published open access in "Clinical Rheumatology": https://link.springer.com/article/10.1007/s10067-017-3954-5. Autologous HSCT may be an appropriate treatment option to [...]

December 23rd, 2017|

“Role of Autoantibodies in Systemic Sclerosis: Relevance in Clinical Practice”

Thomas A. Medsger, Jr., MD University of Pittsburg School of Medicine I just found a recent presentation by Dr. Thomas Medsger on the clinical significance of autoantibodies in systemic scleroderma. [...]

March 31st, 2017|

“Diffuse”? “Limited”? “Overlap”? “Sine”?: Know Your Terms and Your Antibody Type

Background – 25 Years Ago The names used for referring to the scleroderma family of disease are very confusing for a number of reasons. Historically, there were two known forms of [...]

June 21st, 2016|